Package: autoMR
Type: Package
Title: Automated Mendelian Randomization Pipelines and Visualizations
Version: 1.2.1
Authors@R: 
    c(
      person("Kelin", "Zhong", email = "kelinzhonguconn@gmail.com", role = c("aut", "cre")),
      person("Chia-Ling", "Kuo", email = "kuo@uchc.edu", role = "aut")
    )
Maintainer: Kelin Zhong <kelinzhonguconn@gmail.com>
Description: Provides tools to summarize, analyze, and visualize
        results from Mendelian randomization studies using summarized
        genetic association data. The package includes functions for
        generating forest plots and scatter plots at the
        single-nucleotide polymorphism and Mendelian randomization
        method levels, and for fitting multiple estimators in a unified
        pipeline, including inverse-variance weighted estimation,
        Mendelian randomization Egger regression, the weighted median
        estimator, the robust adjusted profile score, Mendelian
        randomization pleiotropy residual sum and outlier, Mendelian
        randomization with the genotype recoding invariance property,
        and a Bayesian horseshoe method. Related methods are described
        by Burgess (2013) <doi:10.1002/gepi.21758>, Bowden (2015)
        <doi:10.1093/ije/dyv080>, Bowden (2016)
        <doi:10.1002/gepi.21965>, Zhao (2020) <doi:10.1214/19-AOS1866>,
        Verbanck (2018) <doi:10.1038/s41588-018-0099-7>, Dudbridge
        (2025) <doi:10.1371/journal.pgen.1011967>, and Grant and
        Burgess (2024) <doi:10.1016/j.ajhg.2023.12.002>. Related
        open-source software includes 'TwoSampleMR'
        <https://github.com/MRCIEU/TwoSampleMR>, 'mr.raps'
        <https://github.com/qingyuanzhao/mr.raps>, 'MR-PRESSO'
        <https://github.com/rondolab/MR-PRESSO>, and 'MR-Horse'
        <https://github.com/aj-grant/mrhorse>.
Depends: R (>= 4.2)
Imports: ggplot2 (>= 4.0.1), dplyr (>= 1.1.4), tidyr (>= 1.3.1),
        MendelianRandomization (>= 0.10.0), R2jags (>= 0.8-9), coda (>=
        0.19-4.1), nortest (>= 1.0-4), grDevices, graphics, stats,
        utils, methods
URL: https://github.com/KelinZhong/autoMR
BugReports: https://github.com/KelinZhong/autoMR/issues
License: GPL-3
Encoding: UTF-8
LazyData: true
RoxygenNote: 7.3.3
Config/pak/sysreqs: cmake libgmp3-dev make jags libicu-dev libuv1-dev
        libssl-dev
Repository: https://kelinzhong.r-universe.dev
Date/Publication: 2026-07-14 17:32:50 UTC
RemoteUrl: https://github.com/kelinzhong/automr
RemoteRef: HEAD
RemoteSha: e566a7a29c346150b4b12e03356ca717a88e34bb
NeedsCompilation: no
Packaged: 2026-10-12 10:00:18 UTC; root
Author: Kelin Zhong [aut, cre],
  Chia-Ling Kuo [aut]